一般来说，出现痘痘主要与皮脂分泌过多、毛囊皮脂腺导管堵塞、细菌感染和炎症反应等因素密切相关。那么，为什么一熬完夜，脸上痘痘就会犹如雨后春笋般涌出？
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一熬夜就长痘痘，实则与人体内分泌有很大关系。熬夜容易导致内分泌紊乱，体内激素分泌失衡，间接造成皮脂分泌过于旺盛，使脱氢表雄酮等雄激素样物质浓度变高，直接刺激皮脂腺分泌过量的皮脂，冲击表皮功能稳态。
而皮肤严重出油、毛孔粗大、痘痘的根本原因就是油脂分泌旺盛，肤色暗沉也跟“油脂分泌旺盛”有关，如下：
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On the other hand, there have been important shortfalls like violating fundamental linear algebra rules all over solving singular matrices and generating matrices with incompatible dimensions.[220]
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